1 keywords

CATH Domain 3hphE00

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.20 Up-down Bundle
Topology 1.20.930 Transcription Elongation Factor S-II; Chain A
Homologous Superfamily 1.20.930.10 Conserved domain common to transcription factors TFIIS, elongin A, CRSP70

Domain Context

CATH Clusters

Superfamily Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
Functional Family PC4 and SFRS1-interacting protein-like isoform X1

Enzyme Information

UniProtKB Entries (2)

O75475
PSIP1_HUMAN
Homo sapiens
PC4 and SFRS1-interacting protein
P35956
POL_VILVK
Visna/maedi virus EV1 KV1772
Gag-Pol polyprotein

PDB Structure

PDB 3HPH
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural basis for functional tetramerization of lentiviral integrase
Hare, S., Di Nunzio, F., Labeja, A., Wang, J., Engelman, A., Cherepanov, P.
Plos Pathog.