CATH Classification

Domain Context

CATH Clusters

Superfamily Microbial ribonucleases
Functional Family Guanyl-specific ribonuclease T1

Enzyme Information

3.1.27.3
Ribonuclease T(1).
based on mapping to UniProt P00651
Two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides ending in G-P with 2',3'-cyclic phosphate intermediates.
-!- Formerly EC 2.7.7.26 and EC 3.1.4.8.

UniProtKB Entries (1)

P00651
RNT1_ASPOR
Aspergillus oryzae RIB40
Guanyl-specific ribonuclease T1

PDB Structure

PDB 3HOH
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Dissection of the structural and functional role of a conserved hydration site in RNase T1.
Langhorst, U., Loris, R., Denisov, V.P., Doumen, J., Roose, P., Maes, D., Halle, B., Steyaert, J.
Protein Sci.