CATH Classification

Domain Context

CATH Clusters

Superfamily Transferase(Phosphotransferase) domain 1
Functional Family Dual specificity protein kinase TTK

Enzyme Information

2.7.12.1
Dual-specificity kinase.
based on mapping to UniProt P33981
ATP + a protein = ADP + a phosphoprotein.
-!- This family of enzymes can phosphorylate both Ser/Thr and Tyr residues. -!- Formerly EC 2.7.1.37.

UniProtKB Entries (1)

P33981
TTK_HUMAN
Homo sapiens
Dual specificity protein kinase TTK

PDB Structure

PDB 3HMN
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Biophysical and X-ray crystallographic analysis of Mps1 kinase inhibitor complexes.
Chu, M.L., Lang, Z., Chavas, L.M., Neres, J., Fedorova, O.S., Tabernero, L., Cherry, M., Williams, D.H., Douglas, K.T., Eyers, P.A.
Biochemistry