CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.120 | 6 Propeller |
|
2.120.10 | Neuraminidase |
|
2.120.10.30 | TolB, C-terminal domain |
Domain Context
CATH Clusters
| Superfamily | TolB, C-terminal domain |
| Functional Family |
Enzyme Information
| 3.1.8.2 |
Diisopropyl-fluorophosphatase.
based on mapping to UniProt Q7SIG4
Diisopropyl fluorophosphate + H(2)O = diisopropyl phosphate + fluoride.
-!- Acts on phosphorus anhydride bonds (such as phosphorus-halide and phosphorus-cyanide) in organophosphorus compounds (including nerve gases). -!- Inhibited by chelating agents. -!- Related to EC 3.1.8.1. -!- Formerly EC 3.8.2.1.
|
UniProtKB Entries (1)
| Q7SIG4 |
DFPA_LOLVU
Loligo vulgaris
Diisopropyl-fluorophosphatase
|
PDB Structure
| PDB | 3HLH |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Reversed enantioselectivity of diisopropyl fluorophosphatase against organophosphorus nerve agents by rational design
J.Am.Chem.Soc.
|