CATH Classification
Domain Context
CATH Clusters
Superfamily | N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 |
Functional Family |
Enzyme Information
1.1.1.35 |
3-hydroxyacyl-CoA dehydrogenase.
based on mapping to UniProt P00348
(S)-3-hydroxyacyl-CoA + NAD(+) = 3-oxoacyl-CoA + NADH.
-!- Also oxidizes S-3-hydroxyacyl-N-acylthioethanolamine and S-3- hydroxyacylhydrolipoate. -!- Some enzymes act, more slowly, with NADP(+). -!- Broad specificity to acyl chain-length (cf. EC 1.1.1.211).
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UniProtKB Entries (1)
P00348 |
HCDH_PIG
Sus scrofa
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial
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PDB Structure
PDB | 3HDH |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Pig heart short chain L-3-hydroxyacyl-CoA dehydrogenase revisited: sequence analysis and crystal structure determination.
Protein Sci.
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