CATH Classification

Domain Context

CATH Clusters

Superfamily Type I PLP-dependent aspartate aminotransferase-like (Major domain)
Functional Family Glutamate decarboxylase

Enzyme Information

4.1.1.15
Glutamate decarboxylase.
based on mapping to UniProt Q42521
L-glutamate = 4-aminobutanoate + CO(2).
-!- The brain enzyme also acts on L-cysteate, 3-sulfino-L-alanine and L-aspartate.

UniProtKB Entries (1)

Q42521
DCE1_ARATH
Arabidopsis thaliana
Glutamate decarboxylase 1

PDB Structure

PDB 3HBX
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
A common structural basis for pH- and calmodulin-mediated regulation in plant glutamate decarboxylase.
Gut, H., Dominici, P., Pilati, S., Astegno, A., Petoukhov, M.V., Svergun, D.I., Grutter, M.G., Capitani, G.
J.Mol.Biol.