CATH Classification

Domain Context

CATH Clusters

Superfamily Glutaredoxin
Functional Family Thioredoxin reductase 3

Enzyme Information

1.8.1.9
Thioredoxin-disulfide reductase.
based on mapping to UniProt Q86VQ6
Thioredoxin + NADP(+) = thioredoxin disulfide + NADPH.
-!- May be identical to EC 1.8.1.10. -!- Formerly EC 1.6.4.5.

UniProtKB Entries (1)

Q86VQ6
TRXR3_HUMAN
Homo sapiens
Thioredoxin reductase 3

PDB Structure

PDB 3H8Q
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of glutaredoxin domain of human thioredoxin reductase 3
Chaikuad, A., Johansson, C., Ugochukwu, E., Roos, A.K., von Delft, F., Pilka, E., Yue, W., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Oppermann, U.
To be Published