CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.70 | Distorted Sandwich |
|
2.70.40 | Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A |
|
2.70.40.10 | Deoxyuridine triphosphatase (dUTPase) |
Domain Context
CATH Clusters
| Superfamily | 2.70.40.10 |
| Functional Family | Deoxyuridine 5'-triphosphate nucleotidohydrolase |
Enzyme Information
| 3.6.1.23 |
dUTP diphosphatase.
based on mapping to UniProt P9WNS5
dUTP + H(2)O = dUMP + diphosphate.
|
UniProtKB Entries (1)
| P9WNS5 |
DUT_MYCTU
Mycobacterium tuberculosis H37Rv
Deoxyuridine 5'-triphosphate nucleotidohydrolase
|
PDB Structure
| PDB | 3H6D |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Direct contacts between conserved motifs of different subunits provide major contribution to active site organization in human and mycobacterial dUTPases.
Febs Lett.
|