CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.260 | 434 Repressor (Amino-terminal Domain) |
|
1.10.260.40 | lambda repressor-like DNA-binding domains |
Domain Context
CATH Clusters
| Superfamily | lambda repressor-like DNA-binding domains |
| Functional Family |
Enzyme Information
| 1.13.11.72 |
2-hydroxyethylphosphonate dioxygenase.
based on mapping to UniProt Q5IW40
2-hydroxyethylphosphonate + O(2) = hydroxymethylphosphonate + formate.
-!- Isolated from some bacteria including Streptomyces hygroscopicus and Streptomyces viridochromogenes. -!- The pro-R hydrogen at C-2 of the ethyl group is retained by the formate ion. -!- Any stereochemistry at C-1 of the ethyl group is lost. -!- One atom from dioxygen is present in each product. -!- Involved in phosphinothricin biosynthesis.
|
UniProtKB Entries (1)
| Q5IW40 |
HEPD_STRVT
Streptomyces viridochromogenes DSM 40736
2-hydroxyethylphosphonate dioxygenase
|
PDB Structure
| PDB | 3GBF |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
An Unusual Carbon-Carbon Bond Cleavage Reaction in the Biosynthesis of the Herbicide Phosphinothricin
To be Published
|