CATH Classification

Domain Context

CATH Clusters

Superfamily Immunoglobulins
Functional Family Ig heavy chain V region 36-60

Enzyme Information

UniProtKB Entries (1)

P00533
EGFR_HUMAN
Homo sapiens
Epidermal growth factor receptor

PDB Structure

PDB 3G5Y
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Antibodies specifically targeting a locally misfolded region of tumor associated EGFR
Garrett, T.P.J., Burgess, A.W., Gan, H.K., Luwor, R.B., Cartwright, G., Walker, F., Orchard, S.G., Clayton, A.H.A., Nice, E.C., Rothacker, J., Catimel, B., Cavenee, W.K., Old, L.J., Stockert, E., Ritter, G., Adams, T.E., Hoyne, P.A., Wittrup, D., Chao, G., Cochran, J.R., Luo, C., Lou, M., Huyton, T., Xu, Y., Fairlie, W.D., Yao, S., Scott, A.M., Johns, T.G.
Proc.Natl.Acad.Sci.USA