CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.150 | Vaccinia Virus protein VP39 |
Domain Context
CATH Clusters
| Superfamily | Vaccinia Virus protein VP39 |
| Functional Family |
Enzyme Information
| 2.1.1.145 |
Trans-aconitate 3-methyltransferase.
based on mapping to UniProt P32643
S-adenosyl-L-methionine + trans-aconitate = S-adenosyl-L-homocysteine + (E)-2-(methoxycarbonylmethyl)butenedioate.
-!- Also catalyzes the formation of the methyl monoester of cis- aconitate, isocitrate and citrate, but more slowly. -!- While the enzyme from Saccharomyces cerevisiae forms (E)-2- (methoxycarbonylmethyl)butenedioate as the product, that from Escherichia coli forms (E)-3-(methoxycarbonyl)-pent-2-enedioate and is therefore classified as a separate enzyme (cf. EC 2.1.1.144).
|
UniProtKB Entries (1)
| P32643 |
TMT1_YEAST
Saccharomyces cerevisiae S288C
Trans-aconitate 3-methyltransferase
|
PDB Structure
| PDB | 3G5T |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structure of trans-aconitate 3-methyltransferase from yeast
To be Published
|