CATH Domain 3g01A01

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.40	Beta Barrel
	2.40.10	Thrombin, subunit H
	2.40.10.10	Trypsin-like serine proteases

Domain Context

CATH Clusters

Superfamily	Trypsin-like serine proteases
Functional Family	Complement factor D

Enzyme Information

3.4.21.-

Serine endopeptidases.

based on mapping to UniProt P08882

UniProtKB Entries (1)

GRAC_MOUSE

Mus musculus

Granzyme C

PDB Structure

PDB	3G01
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structure of granzyme C reveals an unusual mechanism of protease autoinhibition Kaiserman, D., Buckle, A.M., Van Damme, P., Irving, J.A., Law, R.H.P., Matthews, A.Y., Bashtannyk-Puhalovich, T., Langendorf, C., Thompson, P., Vandekerckhove, J., Gevaert, K., Whisstock, J.C., Bird, P.I. Proc.Natl.Acad.Sci.USA