CATH Classification

Domain Context

CATH Clusters

Superfamily Cupredoxins - blue copper proteins
Functional Family

Enzyme Information

1.9.3.1
Cytochrome-c oxidase.
based on mapping to UniProt Q03736
4 ferrocytochrome c + O(2) + 4 H(+) = 4 ferricytochrome c + 2 H(2)O.
-!- The reduction of O(2) to water is accompanied by the extrusion of four protons from the intramitochondrial compartment. -!- Several bacteria appear to contain analogous oxidases.

UniProtKB Entries (1)

Q03736
COX2_RHOSH
Rhodobacter sphaeroides
Cytochrome c oxidase subunit 2

PDB Structure

PDB 3FYI
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Redox dependent conformational changes in cytochrome c oxidase suggest a gating mechanism for proton uptake.
Qin, L., Liu, J., Mills, D., Proshlyakov, D.A., Hiser, C., Ferguson-Miller, S.
Biochemistry