CATH Classification

Domain Context

CATH Clusters

Superfamily 2.80.10.50
Functional Family Botulinum neurotoxin type A

Enzyme Information

3.4.24.69
Bontoxilysin.
based on mapping to UniProt P0DPI1
Limited hydrolysis of proteins of the neuroexocytosis apparatus, synaptobrevins, SNAP25 or syntaxin. No detected action on small molecule substrates.
-!- Belongs to peptidase family M27.

UniProtKB Entries (1)

P0DPI1
BXA1_CLOBH
Clostridium botulinum A str. Hall
Botulinum neurotoxin type A

PDB Structure

PDB 3FUO
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Glycosylated SV2 and gangliosides as dual receptors for botulinum neurotoxin serotype F
Fu, Z., Chen, C., Barbieri, J.T., Kim, J.J., Baldwin, M.R.
Biochemistry