CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.430 | Dihydrofolate Reductase, subunit A |
|
3.40.430.10 | Dihydrofolate Reductase, subunit A |
Domain Context
CATH Clusters
| Superfamily | Dihydrofolate Reductase, subunit A |
| Functional Family | Dihydrofolate reductase |
Enzyme Information
UniProtKB Entries (0)
PDB Structure
| PDB | 3FQF |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structures of wild-type and mutant methicillin-resistant Staphylococcus aureus dihydrofolate reductase reveal an alternate conformation of NADPH that may be linked to trimethoprim resistance.
J.Mol.Biol.
|