CATH Classification

Domain Context

CATH Clusters

Superfamily SET domain
Functional Family Euchromatic histone-lysine N-methyltransferase 2

Enzyme Information

2.1.1.-
Methyltransferases.
based on mapping to UniProt Q9H9B1
2.1.1.43
Histone-lysine N-methyltransferase.
based on mapping to UniProt Q9H9B1
S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].

UniProtKB Entries (1)

Q9H9B1
EHMT1_HUMAN
Homo sapiens
Histone-lysine N-methyltransferase EHMT1

PDB Structure

PDB 3FPD
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural basis for G9a-like protein lysine methyltransferase inhibition by BIX-01294.
Chang, Y., Zhang, X., Horton, J.R., Upadhyay, A.K., Spannhoff, A., Liu, J., Snyder, J.P., Bedford, M.T., Cheng, X.
Nat.Struct.Mol.Biol.