CATH Classification

Domain Context

CATH Clusters

Superfamily Ubiquitin-like 2 activating enzyme e1b. Chain: B, domain 3
Functional Family NEDD8-activating enzyme E1 catalytic subunit, variant

Enzyme Information

6.2.1.-
Acid--thiol ligases.
based on mapping to UniProt Q8TBC4

UniProtKB Entries (1)

Q8TBC4
UBA3_HUMAN
Homo sapiens
NEDD8-activating enzyme E1 catalytic subunit

PDB Structure

PDB 3FN1
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification
Huang, D.T., Ayrault, O., Hunt, H.W., Taherbhoy, A.M., Duda, D.M., Scott, D.C., Borg, L.A., Neale, G., Murray, P.J., Roussel, M.F., Schulman, B.A.
Mol.Cell