CATH Classification

Domain Context

CATH Clusters

Superfamily 2.40.128.20
Functional Family

Enzyme Information

1.7.6.1
Nitrite dismutase.
based on mapping to UniProt Q94734
3 nitrite + 2 H(+) = 2 nitric oxide + nitrate + H(2)O.
-!- The enzyme is one of the nitrophorins from the salivary gland of the blood-feeding insect Rhodnius prolixus. -!- Nitric oxide produced induces vasodilation after injection. -!- Nitrophorins 2 and 4 can also catalyze this reaction.

UniProtKB Entries (1)

Q94734
NP4_RHOPR
Rhodnius prolixus
Nitrophorin-4

PDB Structure

PDB 3FLL
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Effect of mutation of carboxyl side-chain amino acids near the heme on the midpoint potentials and ligand binding constants of nitrophorin 2 and its NO, histamine, and imidazole complexes.
Berry, R.E., Shokhirev, M.N., Ho, A.Y., Yang, F., Shokhireva, T.K., Zhang, H., Weichsel, A., Montfort, W.R., Walker, F.A.
J.Am.Chem.Soc.