CATH Classification

Domain Context

CATH Clusters

Superfamily Butyryl-CoA Dehydrogenase, subunit A, domain 2
Functional Family Nitroalkane oxidase

Enzyme Information

1.7.3.1
Nitroalkane oxidase.
based on mapping to UniProt Q8X1D8
A nitroalkane + H(2)O + O(2) = an aldehyde or ketone + nitrite + H(2)O(2).
-!- While nitroethane may be the physiological substrate, the enzyme also acts on several other nitroalkanes, including 1-nitropropane, 2-nitropropane, 1-nitrobutane, 1-nitropentane, 1-nitrohexane, nitrocyclohexane and some nitroalkanols. -!- Differs from EC 1.13.12.16 in that the preferred substrates are neutral nitroalkanes rather than anionic nitronates.

UniProtKB Entries (1)

Q8X1D8
NAO_FUSOX
Fusarium oxysporum
Nitroalkane oxidase

PDB Structure

PDB 3FCJ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Differential quantum tunneling contributions in nitroalkane oxidase catalyzed and the uncatalyzed proton transfer reaction.
Major, D.T., Heroux, A., Orville, A.M., Valley, M.P., Fitzpatrick, P.F., Gao, J.
Proc.Natl.Acad.Sci.USA