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1 keywords

CATH Domain 3f9iA00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.50 Rossmann fold
Homologous Superfamily 3.40.50.720 NAD(P)-binding Rossmann-like Domain

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family 3-oxoacyl-[acyl-carrier-protein] reductase FabG

Enzyme Information

1.1.1.100
3-oxoacyl-[acyl-carrier-protein] reductase.
based on mapping to UniProt P50941
(3R)-3-hydroxyacyl-[acyl-carrier-protein] + NADP(+) = 3-oxoacyl-[acyl- carrier-protein] + NADPH.
-!- Exhibits a marked preference for [acyl-carrier-protein] derivatives over CoA derivatives as substrates.

UniProtKB Entries (1)

P50941
FABG_RICPR
Rickettsia prowazekii str. Madrid E
3-oxoacyl-[acyl-carrier-protein] reductase FabG

PDB Structure

PDB 3F9I
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of 3-ketoacyl-(acyl-carrier-protein) reductase from Rickettsia prowazekii at 2.25 A resolution.
Subramanian, S., Abendroth, J., Phan, I.Q., Olsen, C., Staker, B.L., Napuli, A., Van Voorhis, W.C., Stacy, R., Myler, P.J.
Acta Crystallogr.,Sect.F
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