CATH Classification

Domain Context

CATH Clusters

Superfamily Protein tyrosine phosphatase superfamily
Functional Family

Enzyme Information

3.1.3.48
Protein-tyrosine-phosphatase.
based on mapping to UniProt P15273
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
-!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.

UniProtKB Entries (1)

P15273
YOPH_YEREN
Yersinia enterocolitica
Tyrosine-protein phosphatase YopH

PDB Structure

PDB 3F99
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Impaired acid catalysis by mutation of a protein loop hinge residue in a YopH mutant revealed by crystal structures.
Brandao, T.A., Robinson, H., Johnson, S.J., Hengge, A.C.
J.Am.Chem.Soc.