CATH Classification

Domain Context

CATH Clusters

Superfamily alpha/beta hydrolase
Functional Family Platelet-activating factor acetylhydrolase

Enzyme Information

3.1.1.47
1-alkyl-2-acetylglycerophosphocholine esterase.
based on mapping to UniProt Q13093
1-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H(2)O = 1-alkyl- sn-glycero-3-phosphocholine + acetate.

UniProtKB Entries (1)

Q13093
PAFA_HUMAN
Homo sapiens
Platelet-activating factor acetylhydrolase

PDB Structure

PDB 3F97
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structures of human group-VIIA phospholipase A2 inhibited by organophosphorus nerve agents exhibit non-aged complexes.
Samanta, U., Kirby, S.D., Srinivasan, P., Cerasoli, D.M., Bahnson, B.J.
Biochem Pharmacol