CATH Classification

Domain Context

CATH Clusters

Superfamily Hmd, C-terminal helical subdomain
Functional Family

Enzyme Information

1.12.98.2
5,10-methenyltetrahydromethanopterin hydrogenase.
based on mapping to UniProt Q58194
H(2) + 5,10-methenyltetrahydromethanopterin = H(+) + 5,10- methylenetetrahydromethanopterin.
-!- Does not catalyze the reduction of artificial dyes. -!- Does not by itself catalyze a H(2)/H(+) exchange reaction. -!- Does not contain nickel or iron-sulfur clusters. -!- Formerly EC 1.12.99.4.

UniProtKB Entries (1)

Q58194
HMD_METJA
Methanocaldococcus jannaschii DSM 2661
5,10-methenyltetrahydromethanopterin hydrogenase

PDB Structure

PDB 3F47
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The crystal structure of C176A mutated [Fe]-hydrogenase suggests an acyl-iron ligation in the active site iron complex.
Hiromoto, T., Ataka, K., Pilak, O., Vogt, S., Stagni, M.S., Meyer-Klaucke, W., Warkentin, E., Thauer, R.K., Shima, S., Ermler, U.
Febs Lett.