CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.450.410
Functional Family

Enzyme Information

4.99.1.2
Alkylmercury lyase.
based on mapping to UniProt P77072
An alkylmercury + H(+) = an alkane + Hg(2+).
-!- Acts on CH(3)Hg(+) and a number of other alkylmercury compounds, in the presence of cysteine or other thiols, liberating mercury as a mercaptide.

UniProtKB Entries (1)

P77072
MERB_ECOLX
Escherichia coli
Alkylmercury lyase

PDB Structure

PDB 3F0O
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structures of the Organomercurial Lyase MerB in Its Free and Mercury-bound Forms: INSIGHTS INTO THE MECHANISM OF METHYLMERCURY DEGRADATION
Lafrance-Vanasse, J., Lefebvre, M., Di Lello, P., Sygusch, J., Omichinski, J.G.
J.Biol.Chem.