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1 keywords

CATH Domain 3ewbX00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.20 Alpha-Beta Barrel
Topology 3.20.20 TIM Barrel
Homologous Superfamily 3.20.20.70 Aldolase class I

Domain Context

CATH Clusters

Superfamily Aldolase class I
Functional Family 2-isopropylmalate synthase

Enzyme Information

2.3.3.13
2-isopropylmalate synthase.
based on mapping to UniProt Q71Y35
Acetyl-CoA + 3-methyl-2-oxobutanoate + H(2)O = (2S)-2-isopropylmalate + CoA.
-!- Formerly EC 4.1.3.12.

UniProtKB Entries (1)

Q71Y35
LEU1_LISMF
Listeria monocytogenes serotype 4b str. F2365
2-isopropylmalate synthase

PDB Structure

PDB 3EWB
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of N-terminal domain of putative 2-isopropylmalate synthase from Listeria monocytogenes.
Ramagopal, U.A., Toro, R., Gilmore, M., Hu, S., Maletic, M., Rodgers, L., Burley, S.K., Almo, S.C.
To be Published
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