CATH Classification

Domain Context

CATH Clusters

Superfamily Aldolase class I
Functional Family 2-isopropylmalate synthase

Enzyme Information

2.3.3.13
2-isopropylmalate synthase.
based on mapping to UniProt Q71Y35
Acetyl-CoA + 3-methyl-2-oxobutanoate + H(2)O = (2S)-2-isopropylmalate + CoA.
-!- Formerly EC 4.1.3.12.

UniProtKB Entries (1)

Q71Y35
LEU1_LISMF
Listeria monocytogenes serotype 4b str. F2365
2-isopropylmalate synthase

PDB Structure

PDB 3EWB
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of N-terminal domain of putative 2-isopropylmalate synthase from Listeria monocytogenes.
Ramagopal, U.A., Toro, R., Gilmore, M., Hu, S., Maletic, M., Rodgers, L., Burley, S.K., Almo, S.C.
To be Published