CATH Classification

Domain Context

CATH Clusters

Superfamily alpha/beta hydrolase
Functional Family Cutinase 1

Enzyme Information

3.1.1.74
Cutinase.
based on mapping to UniProt P00590
Cutin + H(2)O = cutin monomers.
-!- Cutin, a polymeric structural component of plant cuticles, is an hydroxy fatty acid polymer, usually C(16) or C(18) and that contains one to three hydroxyl groups. -!- The enzyme from several fungal sources also hydrolyzes the p-nitrophenyl esters of hexadecanoic acid. -!- It is however inactive toward several esters that are substrates for non-specific esterases.

UniProtKB Entries (1)

P00590
CUTI1_FUSSO
[Nectria] haematococca mpVI
Cutinase 1

PDB Structure

PDB 3ESA
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Solid-state structural characterization of cutinase-ECE-pincer-metal hybrids
Rutten, L., Wieczorek, B., Mannie, J.P.B.A., Kruithof, C.A., Dijkstra, H.P., Egmond, M.R., Lutz, M., Klein Gebbink, R.J.M., Gros, P., van Koten, G.
Chemistry