CATH Domain 3ehbA00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.210	Cytochrome C Oxidase; Chain A
	1.20.210.10	Cytochrome c oxidase-like, subunit I domain

Domain Context

CATH Clusters

Superfamily	Cytochrome c oxidase-like, subunit I domain
Functional Family	Cytochrome c oxidase subunit 1

Enzyme Information

1.9.3.1

Cytochrome-c oxidase.

based on mapping to UniProt P98002

4 ferrocytochrome c + O(2) + 4 H(+) = 4 ferricytochrome c + 2 H(2)O.

-!- The reduction of O(2) to water is accompanied by the extrusion of four protons from the intramitochondrial compartment. -!- Several bacteria appear to contain analogous oxidases.

UniProtKB Entries (2)

P18525	HVM54_MOUSE Mus musculus Ig heavy chain V region 5-84
P08306	COX2_PARDE Paracoccus denitrificans Cytochrome c oxidase subunit 2

PDB Structure

PDB	3EHB
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	A d-pathway mutation decouples the paracoccusdenitrificans cytochrome C oxidase by altering the side-chain orientation of a distant conserved glutamate Durr, K.L., Koepke, J., Hellwig, P., Muller, H., Angerer, H., Peng, G., Olkhova, E., Richter, O.-M.H., Ludwig, B., Michel, H. J.Mol.Biol.