CATH Classification

Domain Context

CATH Clusters

Superfamily Collagenase (Catalytic Domain)
Functional Family

Enzyme Information

3.4.24.19
Procollagen C-endopeptidase.
based on mapping to UniProt P13497
Cleavage of the C-terminal propeptide at Ala-|-Asp in type I and II procollagens and at Arg-|-Asp in type III.
-!- The activity is increased by calcium and by an enhancer glycoprotein.

UniProtKB Entries (1)

P13497
BMP1_HUMAN
Homo sapiens
Bone morphogenetic protein 1

PDB Structure

PDB 3EDH
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural basis for the substrate specificity of bone morphogenetic protein 1/tolloid-like metalloproteases
Mac Sweeney, A., Parrado, S.G., Vinzenz, D., Bernardi, A., Hein, A., Bodendorf, U., Erbel, P., Logel, C., Gerhartz, B.
To be Published