CATH Domain 3ebjB00

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.91	Restriction Endonuclease
	3.40.91.90	Influenza RNA-dependent RNA polymerase subunit PA, endonuclease domain

Domain Context

CATH Clusters

Superfamily	Influenza RNA-dependent RNA polymerase subunit PA, endonuclease domain
Functional Family	Polymerase acidic protein

Enzyme Information

3.1.-.-

Acting on ester bonds.

based on mapping to UniProt Q9Q0U9

UniProtKB Entries (1)

PA_I96A0

Influenza A virus (A/goose/Guangdong/1/1996(H5N1))

Polymerase acidic protein

PDB Structure

PDB	3EBJ
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal structure of an avian influenza polymerase PA(N) reveals an endonuclease active site Yuan, P., Bartlam, M., Lou, Z., Chen, S., Zhou, J., He, X., Lv, Z., Ge, R., Li, X., Deng, T., Fodor, E., Rao, Z., Liu, Y. Nature