CATH Classification

Domain Context

CATH Clusters

Superfamily Nucleic acid-binding proteins
Functional Family Lysine--tRNA ligase

Enzyme Information

6.1.1.6
Lysine--tRNA ligase.
based on mapping to UniProt Q9RHV9
ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys).

UniProtKB Entries (1)

Q9RHV9
SYK_GEOSE
Geobacillus stearothermophilus
Lysine--tRNA ligase

PDB Structure

PDB 3E9H
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Two crystal structures of lysyl-tRNA synthetase from Bacillus stearothermophilus in complex with lysyladenylate-like compounds: insights into the irreversible formation of the enzyme-bound adenylate of L-lysine hydroxamate
Sakurama, H., Takita, T., Mikami, B., Itoh, T., Yasukawa, K., Inouye, K.
J.Biochem.