CATH Classification

Domain Context

CATH Clusters

Superfamily HAD superfamily/HAD-like
Functional Family 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC

Enzyme Information

3.1.3.103
3-deoxy-D-glycero-D-galacto-nonulopyranosonate 9-phosphatase.
based on mapping to UniProt Q8A712
3-deoxy-D-glycero-beta-D-galacto-non-2-ulopyranosonate 9-phosphate + H(2)O = 3-deoxy-D-glycero-beta-D-galacto-non-2-ulopyranosonate + phosphate.
-!- The enzyme, characterized from the bacterium Bacteroides thetaiotaomicron, is part of the biosynthesis pathway of the sialic acid 3-deoxy-D-glycero-beta-D-galacto-non-2-ulopyranosonate (Kdn). -!- Kdn is abundant in extracellular glycoconjugates of lower vertebrates such as fish and amphibians, but is also found in the capsular polysaccharides of bacteria that belong to the Bacteroides genus.

UniProtKB Entries (1)

Q8A712
KDGGP_BACTN
Bacteroides thetaiotaomicron VPI-5482
2-keto-3-deoxy-D-glycero-D-galacto-9-phosphonononic acid phosphatase

PDB Structure

PDB 3E81
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure-Function Analysis of 2-Keto-3-deoxy-D-glycero-D-galactonononate-9-phosphate Phosphatase Defines Specificity Elements in Type C0 Haloalkanoate Dehalogenase Family Members.
Lu, Z., Wang, L., Dunaway-Mariano, D., Allen, K.N.
J.Biol.Chem.