CATH Classification

Domain Context

CATH Clusters

Superfamily Carbonic anhydrase
Functional Family Carbonic anhydrase

Enzyme Information

4.2.1.1
Carbonic anhydrase.
based on mapping to UniProt P45148
H(2)CO(3) = CO(2) + H(2)O.
-!- The enzyme catalyzes the reversible hydration of gaseous CO(2) to carbonic acid, which spontaneously converts to hydrogencarbonate under neutral pH. -!- It is widespread and found in archaea, bacteria, and eukaryotes. -!- Three distinct classes exist, and appear to have evolved independently.

UniProtKB Entries (1)

P45148
CAN_HAEIN
Haemophilus influenzae Rd KW20
Carbonic anhydrase 2

PDB Structure

PDB 3E3F
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Evidence for a bicarbonate "escort" site in Haemophilus influenzae beta-carbonic anhydrase .
Rowlett, R.S., Hoffmann, K.M., Failing, H., Mysliwiec, M.M., Samardzic, D.
Biochemistry