CATH Classification

Domain Context

CATH Clusters

Superfamily Carbonic anhydrase
Functional Family Carbonic anhydrase

Enzyme Information

4.2.1.1
Carbonic anhydrase.
based on mapping to UniProt P45148
H(2)CO(3) = CO(2) + H(2)O.
-!- The enzyme catalyzes the reversible hydration of gaseous CO(2) to carbonic acid, which spontaneously converts to hydrogencarbonate under neutral pH. -!- It is widespread and found in archaea, bacteria, and eukaryotes. -!- Three distinct classes exist, and appear to have evolved independently.

UniProtKB Entries (1)

P45148
CAN_HAEIN
Haemophilus influenzae Rd KW20
Carbonic anhydrase 2

PDB Structure

PDB 3E2A
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Allosteric site variants of Haemophilus influenzae beta-carbonic anhydrase.
Rowlett, R.S., Tu, C., Lee, J., Herman, A.G., Chapnick, D.A., Shah, S.H., Gareiss, P.C.
Biochemistry