CATH Domain 3dscA02

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.110	Translation Initiation Factor IF3
	3.30.110.80	DNA double-strand break repair nuclease

Domain Context

CATH Clusters

Superfamily	DNA double-strand break repair nuclease
Functional Family

Enzyme Information

3.1.-.-

Acting on ester bonds.

based on mapping to UniProt Q8U1N9

UniProtKB Entries (1)

MRE11_PYRFU

Pyrococcus furiosus DSM 3638

DNA double-strand break repair protein Mre11

PDB Structure

PDB	3DSC
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Mre11 dimers coordinate DNA end bridging and nuclease processing in double-strand-break repair. Williams, R.S., Moncalian, G., Williams, J.S., Yamada, Y., Limbo, O., Shin, D.S., Groocock, L.M., Cahill, D., Hitomi, C., Guenther, G., Moiani, D., Carney, J.P., Russell, P., Tainer, J.A. Cell(Cambridge,Mass.)