CATH Classification

Domain Context

CATH Clusters

Superfamily Domain 2, N(10)-formyltetrahydrofolate synthetase
Functional Family Formate--tetrahydrofolate ligase

Enzyme Information

6.3.4.3
Formate--tetrahydrofolate ligase.
based on mapping to UniProt Q9X287
ATP + formate + tetrahydrofolate = ADP + phosphate + 10-formyltetrahydrofolate.
-!- In eukaryotes occurs as a trifunctional enzyme also having EC 1.5.1.5 and EC 3.5.4.9 activity.

UniProtKB Entries (1)

Q9X287
FTHS_THEMA
Thermotoga maritima MSB8
Formate--tetrahydrofolate ligase

PDB Structure

PDB 3DO6
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of Putative Formyltetrahydrofolate Synthetase (TM1766) from THERMOTOGA MARITIMA at 1.85 A resolution
Joint Center for Structural Genomics (JCSG)
To be published