CATH Classification

Domain Context

CATH Clusters

Superfamily RNA-binding S4 domain
Functional Family Pseudouridine synthase

Enzyme Information

5.4.99.21
23S rRNA pseudouridine(2604) synthase.
based on mapping to UniProt P32684
23S rRNA uridine(2604) = 23S rRNA pseudouridine(2604).
-!- The enzyme is not completely specific for uridine(2604) and can, to a small extent, also react with uridine(2605).

UniProtKB Entries (1)

P32684
RLUF_ECOLI
Escherichia coli K-12
23S rRNA pseudouridine(2604) synthase

PDB Structure

PDB 3DH3
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of an RluF-RNA complex: a base-pair rearrangement is the key to selectivity of RluF for U2604 of the ribosome.
Alian, A., DeGiovanni, A., Griner, S.L., Finer-Moore, J.S., Stroud, R.M.
J.Mol.Biol.