1 keywords

CATH Domain 3dh1A00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.140 Cytidine Deaminase; domain 2
Homologous Superfamily 3.40.140.10 Cytidine Deaminase, domain 2

Domain Context

CATH Clusters

Superfamily Cytidine Deaminase, domain 2
Functional Family tRNA-specific adenosine deaminase 2

Enzyme Information

3.5.4.33
tRNA(adenine(34)) deaminase.
based on mapping to UniProt Q7Z6V5
Adenine(34) in tRNA + H(2)O = hypoxanthine(34) in tRNA + NH(3).
-!- The enzyme is involved in editing of tRNA.

UniProtKB Entries (1)

Q7Z6V5
ADAT2_HUMAN
Homo sapiens
TRNA-specific adenosine deaminase 2

PDB Structure

PDB 3DH1
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of human tRNA-specific adenosine-34 deaminase subunit ADAT2.
Welin, M., Tresaugues, L., Andersson, J., Arrowsmith, C.H., Berglund, H., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Karlberg, T., Kotenyova, T., Lehtio, L., Moche, M., Nilsson, M.E., Nyman, T., Olesen, K., Persson, C., Sagemark, J., Schueler, H., Thorsell, A.G., van der Berg, S., Wisniewska, M., Wikstrom, M., Nordlund, P.
To be Published