CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.630 | Aminopeptidase |
|
3.40.630.10 | Zn peptidases |
Domain Context
CATH Clusters
| Superfamily | Zn peptidases |
| Functional Family | Carboxypeptidase B2 |
Enzyme Information
| 3.4.17.20 |
Carboxypeptidase U.
based on mapping to UniProt Q2KIG3
Release of C-terminal Arg and Lys from a polypeptide.
-!- Pro-carboxypeptidase U in plasma is activated by thrombin or plasmin during clotting to form the unstable carboxypeptidase U. -!- Activity similar to that of the more stable lysine carboxypeptidase, except no preference is shown for Lys over Arg. -!- Belongs to peptidase family M14.
|
UniProtKB Entries (1)
| Q2KIG3 |
CBPB2_BOVIN
Bos taurus
Carboxypeptidase B2
|
PDB Structure
| PDB | 3DGV |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The crystal structure of TAFI provides the structural basis for the intrinsic activity of the proenzyme and short half-life of TAFIa
To be Published
|