CATH Classification

Domain Context

CATH Clusters

Superfamily Neutral Protease Domain 2
Functional Family Thermolysin

Enzyme Information

3.4.24.26
Pseudolysin.
based on mapping to UniProt P14756
Hydrolysis of proteins including elastin, collagen types III and IV, fibronectin and immunoglobulin A, generally with bulky hydrophobic group at P1'. Insulin B chain cleavage pattern identical to that of thermolysin, but specificity differs in other respects.
-!- Causes tissue damage. -!- Belongs to peptidase family M4. -!- Formerly EC 3.4.24.4.

UniProtKB Entries (1)

P14756
ELAS_PSEAE
Pseudomonas aeruginosa PAO1
Elastase

PDB Structure

PDB 3DBK
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of the Elastase of Pseudomonas aeruginosa Complexed with Phosphoramidon
Overgaard, M.T., McKay, D.B.
To be Published