CATH Domain 3datA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.430	Dihydrofolate Reductase, subunit A
	3.40.430.10	Dihydrofolate Reductase, subunit A

Domain Context

CATH Clusters

Superfamily	Dihydrofolate Reductase, subunit A
Functional Family	Dihydrofolate reductase

Enzyme Information

UniProtKB Entries (1)

Q81R22_BACAN

Bacillus anthracis

Dihydrofolate reductase

PDB Structure

PDB	3DAT
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	X-ray structure of the ternary MTX.NADPH complex of the anthrax dihydrofolate reductase: a pharmacophore for dual-site inhibitor design. Bennett, B.C., Wan, Q., Ahmad, M.F., Langan, P., Dealwis, C.G. J.Struct.Biol.