CATH Classification

Domain Context

CATH Clusters

Superfamily Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal)
Functional Family DNA-3-methyladenine glycosylase 2

Enzyme Information

3.2.2.21
DNA-3-methyladenine glycosylase II.
based on mapping to UniProt P04395
Hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine.

UniProtKB Entries (1)

P04395
3MG2_ECOLI
Escherichia coli K-12
DNA-3-methyladenine glycosylase 2

PDB Structure

PDB 3CWS
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of the E. coli DNA Glycosylase AlkA Bound to the Ends of Duplex DNA: A System for the Structure Determination of Lesion-Containing DNA.
Bowman, B.R., Lee, S., Wang, S., Verdine, G.L.
Structure