CATH Classification

Domain Context

CATH Clusters

Superfamily Rieske [2Fe-2S] iron-sulphur domain
Functional Family Cytochrome b-c1 complex subunit Rieske

Enzyme Information

1.10.2.2
Quinol--cytochrome-c reductase.
based on mapping to UniProt Q5ZLR5
Quinol + 2 ferricytochrome c = quinone + 2 ferrocytochrome c + 2 H(+).
-!- The enzyme, often referred to as the cytochrome bc1 complex or complex III, is the third complex in the electron transport chain. -!- It is present in the mitochondria of all aerobic eukaryotes and in the inner membranes of most bacteria. -!- The mammalian enzyme contains cytochromes b-562, b-566 and C(1), and a 2-iron ferredoxin. -!- Depending on the organism and physiological conditions, the enzyme extrudes either two or four protons from the cytoplasmic to the non- cytoplasmic compartment (cf. EC 1.6.99.3).

UniProtKB Entries (1)

D0VX32
D0VX32_CHICK
Gallus gallus
Mitochondrial ubiquinol-cytochrome c reductase ubiquinone-binding protein qp-c

PDB Structure

PDB 3CWB
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The role of molecular modeling in the design of analogues of the fungicidal natural products crocacins A and D.
Crowley, P.J., Berry, E.A., Cromartie, T., Daldal, F., Godfrey, C.R., Lee, D.W., Phillips, J.E., Taylor, A., Viner, R.
Bioorg.Med.Chem.