CATH Classification

Domain Context

CATH Clusters

Superfamily D-Amino Acid Oxidase, subunit A, domain 2
Functional Family D-amino-acid oxidase

Enzyme Information

1.4.3.3
D-amino-acid oxidase.
based on mapping to UniProt P14920
A D-amino acid + H(2)O + O(2) = a 2-oxo acid + NH(3) + H(2)O(2).
-!- Wide specificity for D-amino acids. -!- Also acts on glycine.

UniProtKB Entries (1)

P14920
OXDA_HUMAN
Homo sapiens
D-amino-acid oxidase

PDB Structure

PDB 3CUK
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The discovery of fused pyrrole carboxylic acids as novel, potent D-amino acid oxidase (DAO) inhibitors.
Sparey, T., Abeywickrema, P., Almond, S., Brandon, N., Byrne, N., Campbell, A., Hutson, P.H., Jacobson, M., Jones, B., Munshi, S., Pascarella, D., Pike, A., Prasad, G.S., Sachs, N., Sakatis, M., Sardana, V., Venkatraman, S., Young, M.B.
Bioorg.Med.Chem.Lett.