CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.70.330
Functional Family Poly(A)-specific ribonuclease PARN

Enzyme Information

3.1.13.4
Poly(A)-specific ribonuclease.
based on mapping to UniProt O95453
Exonucleolytic cleavage of poly(A) to 5'-AMP.
-!- Cleaves poly(A) in either the single- or double-stranded form.

UniProtKB Entries (1)

O95453
PARN_HUMAN
Homo sapiens
Poly(A)-specific ribonuclease PARN

PDB Structure

PDB 3CTR
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of the RRM domain of poly(A)-specific ribonuclease reveals a novel m(7)G-cap-binding mode.
Monecke, T., Schell, S., Dickmanns, A., Ficner, R.
J.Mol.Biol.