CATH Classification

Domain Context

CATH Clusters

Superfamily Bira Bifunctional Protein; Domain 2
Functional Family Phenylalanyl-tRNA synthetase 2, mitochondrial

Enzyme Information

6.1.1.20
Phenylalanine--tRNA ligase.
based on mapping to UniProt O95363
ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl- tRNA(Phe).

UniProtKB Entries (1)

O95363
SYFM_HUMAN
Homo sapiens
Phenylalanine--tRNA ligase, mitochondrial

PDB Structure

PDB 3CMQ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The tRNA-Induced Conformational Activation of Human Mitochondrial Phenylalanyl-tRNA Synthetase.
Klipcan, L., Levin, I., Kessler, N., Moor, N., Finarov, I., Safro, M.
Structure