|3.90.770||3-hydroxy-3-methylglutaryl-coenzyme A Reductase; Chain A, domain 2|
|3.90.770.10||3-hydroxy-3-methylglutaryl-coenzyme A Reductase; Chain A, domain 2|
|Superfamily||3-hydroxy-3-methylglutaryl-coenzyme A Reductase; Chain A, domain 2|
|Functional Family||3-hydroxy-3-methylglutaryl coenzyme A reductase|
Hydroxymethylglutaryl-CoA reductase (NADPH).
based on mapping to UniProt P04035
(R)-mevalonate + CoA + 2 NADP(+) = (S)-3-hydroxy-3-methylglutaryl-CoA + 2 NADPH.
UniProtKB Entries (1)
3-hydroxy-3-methylglutaryl-coenzyme A reductase
Thermodynamic and structure guided design of statin based inhibitors of 3-hydroxy-3-methylglutaryl coenzyme a reductase.