CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.60 | Sandwich |
|
2.60.40 | Immunoglobulin-like |
|
2.60.40.2020 |
Domain Context
CATH Clusters
| Superfamily | 2.60.40.2020 |
| Functional Family | Cysteine peptidase inhibitor |
Enzyme Information
UniProtKB Entries (2)
| Q966X9 |
CHAG_TRYCR
Trypanosoma cruzi
Chagasin
|
| P07858 |
CATB_HUMAN
Homo sapiens
Cathepsin B
|
PDB Structure
| PDB | 3CBJ |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Displacement of the occluding loop by the parasite protein, chagasin, results in efficient inhibition of human cathepsin B.
J.Biol.Chem.
|