CATH Classification
| Level | CATH Code | Description | 
|---|---|---|
 
	 | 
    2 | Mainly Beta | 
 
	 | 
    2.80 | Trefoil | 
 
	 | 
    2.80.10 | Trefoil (Acidic Fibroblast Growth Factor, subunit A) | 
 
	 | 
    2.80.10.50 | 
Domain Context
CATH Clusters
| Superfamily | 2.80.10.50 | 
| Functional Family | 
Enzyme Information
| 3.2.2.22 | 
							 rRNA N-glycosylase. 
							based on mapping to UniProt P33183 		
							Endohydrolysis of the N-glycosidic bond at one specific adenosine on the 28S rRNA. 
							-!- Ricin A-chain and related toxins show this activity. -!- Naked rRNA is attacked more slowly than rRNA in intact ribosomes. -!- Naked rRNA from Escherichia coli is cleaved at a corresponding position. 
						 | 
					
UniProtKB Entries (1)
| P33183 | 
						 NIGB_SAMNI 
						Sambucus nigra 
						Nigrin b 
					 | 
				
PDB Structure
| PDB | 3CA6 | 
| External Links | |
| Method | X-RAY DIFFRACTION | 
| Organism | |
| Primary Citation | 
					 Structural basis for sugar recognition, including the Tn carcinoma antigen, by the lectin SNA-II from Sambucus nigra 
					    
					    Proteins 
					    
					 | 
			
