CATH Classification

Domain Context

CATH Clusters

Superfamily 1.20.1260.10
Functional Family Non-heme ferritin

Enzyme Information

1.16.3.2
Bacterial non-heme ferritin.
based on mapping to UniProt Q9ZLI1
4 Fe(2+) + O(2) + 6 H(2)O = 4 (FeO(OH)) + 8 H(+).
-!- Ferritins are intracellular iron-storage and detoxification proteins found in all kingdoms of life. -!- They are formed from two subunits that co-assemble in various ratios to form a spherical protein shell. -!- Thousands of mineralized iron atoms are stored within the core of the structure. -!- The product of dioxygen reduction by the bacterial non-heme ferritin is hydrogen peroxide, which is consumed in a subsequent reaction.

UniProtKB Entries (1)

Q9ZLI1
FTN_HELPJ
Helicobacter pylori J99
Bacterial non-heme ferritin

PDB Structure

PDB 3BVF
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural basis for the iron uptake mechanism of Helicobacter pylori ferritin
Kim, K.H., Cho, K.J., Lee, J.H., Shin, H.J., Yang, I.S.
To be Published