CATH Classification

Domain Context

CATH Clusters

Superfamily Ricin (A Subunit), domain 2
Functional Family Ricin

Enzyme Information

3.2.2.22
rRNA N-glycosylase.
based on mapping to UniProt P02879
Endohydrolysis of the N-glycosidic bond at one specific adenosine on the 28S rRNA.
-!- Ricin A-chain and related toxins show this activity. -!- Naked rRNA is attacked more slowly than rRNA in intact ribosomes. -!- Naked rRNA from Escherichia coli is cleaved at a corresponding position.

UniProtKB Entries (1)

P02879
RICI_RICCO
Ricinus communis
Ricin

PDB Structure

PDB 3BJG
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of Rivax: A Human Ricin Vaccine
Legler, P.M., Brey, R.N., Vitteta, E.S., Millard, C.B.
To be Published